The second season picks up where the first left off. Rex is dead, and, new neighbors, the Applewhites have moved in. Gabrielle, Lynette, and Susan attempt to comfort Bree while Phyllis, Rex’s mother, arrives on Wisteria Lane. Meanwhile Mike and Susan deal with Zach while Gabrielle struggles with the two men in her life.

Susan is surprised, and not pleasantly so, when she finds out who Edie’s new boyfriend is—her ex-husband Karl. Meanwhile Lynette goes back to work, leaving Tom at home in charge of the house, which turns out to be a better plan in theory. Lynette has a problem of getting Tom to keep the house clean [...]

Bree’s mother-in-law, Phyllis (guest star Shirley Knight), gets her in trouble with the law, Susan tries bravely to accept Edie’s new role in Julie’s life, Lynette’s demanding boss (guest star Joely Fisher) makes her miss Parker’s first day of kindergarten. Bree later on takes a polygraph test to prove her innocence in Rex’s death and [...]

On one of Gabrielle’s prison visits to see Carlos she creates a terrible riot, which lands Carlos in hot water. Gabrielle meets an interesting attorney whom she is attracted to. Also, Susan puts her feelings aside and joins Mike in searching for his son Zach, although Susan finds Zach when alone. She learns of his [...]

Susan’s longtime book agent and dear friend, Lonny Moon (guest star Wallace Shawn), gets into financial trouble. Lynette is forced to go out to bars night after night with her man-hungry boss, Nina (guest star Joely Fisher). Also, Bree re-buries Rex amid police suspicions. Bree also finds out about Rex’s feelings about her prior to [...]

Mike and Susan face a crisis in their relationship when Susan tries to get Paul Young arrested by confessing to a police officer that he killed Mrs. Huber and Mike has her diaries as proof. The officer goes over to Mike to get the story, but Mike denies the whole thing. Later, Susan’s mother pays [...]

Gabrielle tries to revisit her past when old friends come to town, but doesn’t want anyone to know that she’s three months pregnant when getting dressed up. With the aftermath of her breakup with Mike, Susan finds temporary solace from her ex-husband Karl as his relationship with Edie hits a bump. Also, the Scavo family [...]

All of Wisteria Lane is panicked by a burglar loose in the neighborhood; a neighborhood watch committee is formed; Bree finds out some disturbing information about George; Sophie (guest star Lesley Ann Warren) and Morty (guest star Bob Newhart) get married; at the wedding, Susan learns who her real father is and is determined to [...]

George stalks Bree, despite her efforts to break up with him. Lynette takes charge of office politics. Carlos is paroled from prison and returns a new man, and Gabrielle is jealous of his new ‘holier-than-thou’ confidante. Susan meets her birth father and tries to begin a relationship with him.

Lynette tries to put a daycare center in Parcher & Murphy by recruiting employees’ children to get the program started. Gabrielle and Sister Mary Bernard (guest star Melinda Page Hamilton) face off over Carlos’ mission of mercy to Africa. Bree brings Andrew home and tells him about the revelation of George poisoning his father Rex [...]